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A novel computational strategy for DNA methylation imputation using mixture regression model (MRM)
BACKGROUND: DNA methylation is an important heritable epigenetic mark that plays a crucial role in transcriptional regulation and the pathogenesis of various human disorders. The commonly used DNA methylation measurement approaches, e.g., Illumina Infinium HumanMethylation-27 and -450 BeadChip array...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708217/ https://www.ncbi.nlm.nih.gov/pubmed/33261550 http://dx.doi.org/10.1186/s12859-020-03865-z |