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The Immunostimulative Effect and Mechanisms of a Novel Mouse Anti-Human PD-1 Monoclonal Antibody on Jurkat Lymphocytic Cells Cocultured with Hepatoma Cells

BACKGROUND: Monoclonal antibodies (mAbs) that target the programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) immune checkpoint have demonstrated substantial clinical benefit for a variety of solid tumors. However, their applications in patients with hepatocellular carcinoma (HCC) are re...

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Detalles Bibliográficos
Autores principales: Li, Ziwei, Li, Bin, Li, Li, Wang, Guanying, Li, Yuanyuan, Fu, Ruoqiu, Ming, Yue, Ni, Rui, Wang, Jiming, Ye, George, Chen, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708315/
https://www.ncbi.nlm.nih.gov/pubmed/33273828
http://dx.doi.org/10.2147/OTT.S281397