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The Immunostimulative Effect and Mechanisms of a Novel Mouse Anti-Human PD-1 Monoclonal Antibody on Jurkat Lymphocytic Cells Cocultured with Hepatoma Cells
BACKGROUND: Monoclonal antibodies (mAbs) that target the programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) immune checkpoint have demonstrated substantial clinical benefit for a variety of solid tumors. However, their applications in patients with hepatocellular carcinoma (HCC) are re...
Autores principales: | Li, Ziwei, Li, Bin, Li, Li, Wang, Guanying, Li, Yuanyuan, Fu, Ruoqiu, Ming, Yue, Ni, Rui, Wang, Jiming, Ye, George, Chen, Jianhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708315/ https://www.ncbi.nlm.nih.gov/pubmed/33273828 http://dx.doi.org/10.2147/OTT.S281397 |
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