Activation of PAR2 by tissue factor induces the release of the PTEN from MAGI proteins and regulates PTEN and Akt activities

Tissue factor (TF) signalling has been associated with alterations in Akt activity influencing cellular survival and proliferation. TF is also shown to induce signalling through activation of the protease activated receptor (PAR)2. Seven cell lines were exposed to recombinant-TF (rec-TF), or activat...

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Detalles Bibliográficos
Autores principales: Mohammad, Mohammad A., Greenman, John, Maraveyas, Anthony, Ettelaie, Camille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708427/
https://www.ncbi.nlm.nih.gov/pubmed/33262514
http://dx.doi.org/10.1038/s41598-020-77963-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708427/
https://www.ncbi.nlm.nih.gov/pubmed/33262514
http://dx.doi.org/10.1038/s41598-020-77963-6

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