(18)F-meta-fluorobenzylguanidine ((18)F-mFBG) to monitor changes in norepinephrine transporter expression in response to therapeutic intervention in neuroblastoma models

Targeted radiotherapy with (131)I-mIBG, a substrate of the human norepinephrine transporter (NET-1), shows promising responses in heavily pre-treated neuroblastoma (NB) patients. Combinatorial approaches that enhance (131)I-mIBG tumour uptake are of substantial clinical interest but biomarkers of re...

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Detalles Bibliográficos
Autores principales: Turnock, Stephen, Turton, David R., Martins, Carlos Daniel, Chesler, Louis, Wilson, Thomas C., Gouverneur, Véronique, Smith, Graham, Kramer-Marek, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708446/
https://www.ncbi.nlm.nih.gov/pubmed/33262374
http://dx.doi.org/10.1038/s41598-020-77788-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708446/
https://www.ncbi.nlm.nih.gov/pubmed/33262374
http://dx.doi.org/10.1038/s41598-020-77788-3

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