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Deep learning suggests that gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure

Understanding the genetic regulatory code governing gene expression is an important challenge in molecular biology. However, how individual coding and non-coding regions of the gene regulatory structure interact and contribute to mRNA expression levels remains unclear. Here we apply deep learning on...

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Detalles Bibliográficos
Autores principales: Zrimec, Jan, Börlin, Christoph S., Buric, Filip, Muhammad, Azam Sheikh, Chen, Rhongzen, Siewers, Verena, Verendel, Vilhelm, Nielsen, Jens, Töpel, Mats, Zelezniak, Aleksej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708451/
https://www.ncbi.nlm.nih.gov/pubmed/33262328
http://dx.doi.org/10.1038/s41467-020-19921-4