The retinal toxicity profile towards assemblies of Amyloid-β indicate the predominant pathophysiological activity of oligomeric species

Amyloid-β (Aβ), reported as a significant constituent of drusen, was implicated in the pathophysiology of age-related macular degeneration (AMD), yet the identity of the major pathogenic Aβ species in the retina has remained hitherto unclear. Here, we examined the in-vivo retinal impact of distinct...

Descripción completa

Detalles Bibliográficos
Autores principales: Naaman, Efrat, Ya’ari, Sarah, Itzkovich, Chen, Safuri, Shadi, Macsi, Flora, Kellerman, Lior, Mimouni, Michael, Mann, Irit, Gazit, Ehud, Adler-Abramovich, Lihi, Zayit-Soudry, Shiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708452/
https://www.ncbi.nlm.nih.gov/pubmed/33262378
http://dx.doi.org/10.1038/s41598-020-77712-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708452/
https://www.ncbi.nlm.nih.gov/pubmed/33262378
http://dx.doi.org/10.1038/s41598-020-77712-9

Ejemplares similares