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Multiple proteases are involved in mesothelin shedding by cancer cells
Mesothelin (MSLN) is a lineage restricted cell surface protein expressed in about 30% of human cancers and high MSLN expression is associated with poor survival in several different cancers. The restricted expression of MSLN in normal tissue and its frequent expression in cancers make MSLN an excell...
Autores principales: | Liu, Xiufen, Chan, Alexander, Tai, Chin-Hsien, Andresson, Thorkell, Pastan, Ira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708464/ https://www.ncbi.nlm.nih.gov/pubmed/33262421 http://dx.doi.org/10.1038/s42003-020-01464-5 |
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