Cargando…
Gap junctions amplify spatial variations in cell volume in proliferating tumor spheroids
Sustained proliferation is a significant driver of cancer progression. Cell-cycle advancement is coupled with cell size, but it remains unclear how multiple cells interact to control their volume in 3D clusters. In this study, we propose a mechano-osmotic model to investigate the evolution of volume...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708487/ https://www.ncbi.nlm.nih.gov/pubmed/33262337 http://dx.doi.org/10.1038/s41467-020-19904-5 |