Targeting the coronavirus SARS-CoV-2: computational insights into the mechanism of action of the protease inhibitors lopinavir, ritonavir and nelfinavir

Coronavirus SARS-CoV-2 is a recently discovered single-stranded RNA betacoronavirus, responsible for a severe respiratory disease known as coronavirus disease 2019, which is rapidly spreading. Chinese health authorities, as a response to the lack of an effective therapeutic strategy, started to inve...

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Detalles Bibliográficos
Autores principales: Bolcato, Giovanni, Bissaro, Maicol, Pavan, Matteo, Sturlese, Mattia, Moro, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708625/
https://www.ncbi.nlm.nih.gov/pubmed/33262359
http://dx.doi.org/10.1038/s41598-020-77700-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708625/
https://www.ncbi.nlm.nih.gov/pubmed/33262359
http://dx.doi.org/10.1038/s41598-020-77700-z

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