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Targeting the coronavirus SARS-CoV-2: computational insights into the mechanism of action of the protease inhibitors lopinavir, ritonavir and nelfinavir
Coronavirus SARS-CoV-2 is a recently discovered single-stranded RNA betacoronavirus, responsible for a severe respiratory disease known as coronavirus disease 2019, which is rapidly spreading. Chinese health authorities, as a response to the lack of an effective therapeutic strategy, started to inve...
Autores principales: | Bolcato, Giovanni, Bissaro, Maicol, Pavan, Matteo, Sturlese, Mattia, Moro, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708625/ https://www.ncbi.nlm.nih.gov/pubmed/33262359 http://dx.doi.org/10.1038/s41598-020-77700-z |
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