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Inhibition of EZH2 ameliorates bacteria-induced liver injury by repressing RUNX1 in dendritic cells

Fulminant hepatic failure (FHF) is a clinical syndrome characterized by a sudden and severe impairment in liver function. However, the precise mechanism of immune dysregulation that is significant to FHF pathogenesis remains unclear. Enhancer of zeste homolog 2 (EZH2) has been implicated in inflamma...

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Detalles Bibliográficos
Autores principales: Wang, Yanan, Wang, Qiwei, Wang, Bei, Gu, Yuting, Yu, Hongshuang, Yang, Wanlin, Ren, Xiaohui, Qian, Fengtao, Zhao, Xiaonan, Xiao, Yichuan, Zhang, Yanyun, Jin, Min, Zhu, Meiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708645/
https://www.ncbi.nlm.nih.gov/pubmed/33262329
http://dx.doi.org/10.1038/s41419-020-03219-w