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A selected small molecule prevents inflammatory osteolysis through restraining osteoclastogenesis by modulating PTEN activity

BACKGROUND: Inflammatory osteolysis is a severe infectious bone disorder that occurs during orthopaedic surgery and is caused by disruptions in the dynamic balance of bone matrix homeostasis, which makes this condition a burden on surgical procedures. Developing novel therapeutic drugs about inhibit...

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Detalles Bibliográficos
Autores principales: Chen, Yueqi, Hu, Wenhui, Wang, Yiran, Li, Yuheng, Li, Xiaoming, Li, Haibo, Tang, Yong, Zhang, Lincheng, Dong, Yutong, Yang, Xiaochao, Wei, Ye, Dong, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708775/
https://www.ncbi.nlm.nih.gov/pubmed/33377656
http://dx.doi.org/10.1002/ctm2.240