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A selected small molecule prevents inflammatory osteolysis through restraining osteoclastogenesis by modulating PTEN activity
BACKGROUND: Inflammatory osteolysis is a severe infectious bone disorder that occurs during orthopaedic surgery and is caused by disruptions in the dynamic balance of bone matrix homeostasis, which makes this condition a burden on surgical procedures. Developing novel therapeutic drugs about inhibit...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708775/ https://www.ncbi.nlm.nih.gov/pubmed/33377656 http://dx.doi.org/10.1002/ctm2.240 |