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Effects of Saikosaponin D on CYP1A2 and CYP2D6 in HepaRG Cells

BACKGROUND: Bupleurum is one of the most important traditional Chinese medicines and an ingredient in many compound preparations. It is widely used together with other drugs in clinical practice, and thus there is great potential for drug–drug interactions. Saikosaponin D (SsD) is a major bioactive...

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Detalles Bibliográficos
Autores principales: Li, Hongfang, Tang, Yunyan, Wang, Yang, Wei, Weipeng, Yin, Chengchen, Tang, Fushang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708782/
https://www.ncbi.nlm.nih.gov/pubmed/33273809
http://dx.doi.org/10.2147/DDDT.S268358