Cargando…

Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice

Cellular antioxidants protect against hyperoxic lung injury. The role of the glutathione (GSH) system in lung development and bronchopulmonary dysplasia (BPD) pathogenesis has not been systematically investigated. The current study utilized GSH reductase-deficient (Gsr-KO) neonatal mice to test the...

Descripción completa

Detalles Bibliográficos
Autores principales: Robbins, Mary E., Cho, Hye-Youn, Hansen, Jason M., Luchsinger, Joseph R., Locy, Morgan L., Velten, Markus, Kleeberger, Steven R., Rogers, Lynette K., Tipple, Trent E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708869/
https://www.ncbi.nlm.nih.gov/pubmed/33254076
http://dx.doi.org/10.1016/j.redox.2020.101797