Dissecting the binding mechanisms of transcription factors to DNA using a statistical thermodynamics framework

Transcription Factors (TFs) bind to DNA and control activity of target genes. Here, we present ChIPanalyser, a user-friendly, versatile and powerful R/Bioconductor package predicting and modelling the binding of TFs to DNA. ChIPanalyser performs similarly to state-of-the-art tools, but is an explain...

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Detalles Bibliográficos
Autores principales: Martin, Patrick C.N., Zabet, Nicolae Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708957/
https://www.ncbi.nlm.nih.gov/pubmed/33304457
http://dx.doi.org/10.1016/j.csbj.2020.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708957/
https://www.ncbi.nlm.nih.gov/pubmed/33304457
http://dx.doi.org/10.1016/j.csbj.2020.11.006

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