Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity

Autoimmune connective tissue diseases arise in a stepwise fashion from asymptomatic preclinical autoimmunity. Type I interferons have a crucial role in the progression to established autoimmune diseases. The cellular source and regulation in disease initiation of these cytokines is not clear, but pl...

Descripción completa

Detalles Bibliográficos
Autores principales: Psarras, Antonios, Alase, Adewonuola, Antanaviciute, Agne, Carr, Ian M., Md Yusof, Md Yuzaiful, Wittmann, Miriam, Emery, Paul, Tsokos, George C., Vital, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708979/
https://www.ncbi.nlm.nih.gov/pubmed/33262343
http://dx.doi.org/10.1038/s41467-020-19918-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708979/
https://www.ncbi.nlm.nih.gov/pubmed/33262343
http://dx.doi.org/10.1038/s41467-020-19918-z

Ejemplares similares