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Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity
Autoimmune connective tissue diseases arise in a stepwise fashion from asymptomatic preclinical autoimmunity. Type I interferons have a crucial role in the progression to established autoimmune diseases. The cellular source and regulation in disease initiation of these cytokines is not clear, but pl...
Autores principales: | Psarras, Antonios, Alase, Adewonuola, Antanaviciute, Agne, Carr, Ian M., Md Yusof, Md Yuzaiful, Wittmann, Miriam, Emery, Paul, Tsokos, George C., Vital, Edward M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708979/ https://www.ncbi.nlm.nih.gov/pubmed/33262343 http://dx.doi.org/10.1038/s41467-020-19918-z |
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