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The influence of rat strain on the development of neuropathic pain and comorbid anxio-depressive behaviour after nerve injury
Back-translating the clinical manifestations of human disease burden into animal models is increasingly recognized as an important facet of preclinical drug discovery. We hypothesized that inbred rat strains possessing stress hyper-reactive-, depressive- or anxiety-like phenotypes may possess more t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708988/ https://www.ncbi.nlm.nih.gov/pubmed/33262364 http://dx.doi.org/10.1038/s41598-020-77640-8 |