Cargando…

The influence of rat strain on the development of neuropathic pain and comorbid anxio-depressive behaviour after nerve injury

Back-translating the clinical manifestations of human disease burden into animal models is increasingly recognized as an important facet of preclinical drug discovery. We hypothesized that inbred rat strains possessing stress hyper-reactive-, depressive- or anxiety-like phenotypes may possess more t...

Descripción completa

Detalles Bibliográficos
Autores principales: Hestehave, Sara, Abelson, Klas S. P., Brønnum Pedersen, Tina, Finn, David P., Andersson, Daniel R., Munro, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708988/
https://www.ncbi.nlm.nih.gov/pubmed/33262364
http://dx.doi.org/10.1038/s41598-020-77640-8