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First report of (68)Ga-PRGD2 PET/MRI molecular imaging of vaso-occlusion in a patient with sickle cell disease

Increased vascular cell adhesion (hyperadhesion) to the endothelium is responsible for the hallmark acute pain episodes, or vaso-occlusive crises (VOC), of sickle cell disease. The integrin α(v)β(3) plays an important role in VOC since it mediates sickle red blood cell adhesion to the endothelium, a...

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Detalles Bibliográficos
Autores principales: Novelli, Enrico M, Moon, Chan Hong, Pham, Tiffany A, Perkins, Lydia A, Little-Ihrig, Lynda, Tavakoli, Sina, Mason, N. Scott, Lang, Lixin, Chen, Xiaoyuan, Laymon, Charles M, Gladwin, Mark T, Anderson, Carolyn J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709053/
https://www.ncbi.nlm.nih.gov/pubmed/33299586
http://dx.doi.org/10.1259/bjrcr.20200024