Anti gC1qR/p32/HABP1 Antibody Therapy Decreases Tumor Growth in an Orthotopic Murine Xenotransplant Model of Triple Negative Breast Cancer

gC1qR is highly expressed in breast cancer and plays a role in cancer cell proliferation. This study explored therapy with gC1qR monoclonal antibody 60.11, directed against the C1q binding domain of gC1qR, in a murine orthotopic xenotransplant model of triple negative breast cancer. MDA231 breast ca...

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Detalles Bibliográficos
Autores principales: Peerschke, Ellinor I., de Stanchina, Elisa, Chang, Qing, Manova-Todorova, Katia, Barlas, Afsar, Savitt, Anne G., Geisbrecht, Brian V., Ghebrehiwet, Berhane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709104/
https://www.ncbi.nlm.nih.gov/pubmed/33036212
http://dx.doi.org/10.3390/antib9040051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709104/
https://www.ncbi.nlm.nih.gov/pubmed/33036212
http://dx.doi.org/10.3390/antib9040051

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