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Mitochondrion as a Selective Target for the Treatment of Atherosclerosis: Role of Mitochondrial DNA Mutations and Defective Mitophagy in the Pathogenesis of Atherosclerosis and Chronic Inflammation

BACKGROUND: Atherosclerosis is a chronic inflammatory condition that affects different arteries in the human body and often leads to severe neurological complications, such as stroke and its sequelae. Affected blood vessels develop atherosclerotic lesions in the form of focal thickening of the intim...

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Detalles Bibliográficos
Autores principales: Orekhov, Alexander N., Poznyak, Anastasia V., Sobenin, Igor A., Nikifirov, Nikita N., Ivanova, Ekaterina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709151/
https://www.ncbi.nlm.nih.gov/pubmed/31744449
http://dx.doi.org/10.2174/1570159X17666191118125018