Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain

Nucleocapsid protein (N) is the most abundant viral protein encoded by SARS-CoV-2, the causative agent of COVID-19. N plays key roles at different steps in the replication cycle and is used as a serological marker of infection. Here we characterize the biochemical properties of SARS-CoV-2 N. We defi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Chao, Qavi, Abraham J., Hachim, Asmaa, Kavian, Niloufar, Cole, Aidan R., Moyle, Austin B., Wagner, Nicole D., Sweeney-Gibbons, Joyce, Rohrs, Henry W., Gross, Michael L., Peiris, J. S. Malik, Basler, Christopher F., Farnsworth, Christopher W., Valkenburg, Sophie A., Amarasinghe, Gaya K., Leung, Daisy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709165/
https://www.ncbi.nlm.nih.gov/pubmed/33269347
http://dx.doi.org/10.1101/2020.11.30.404905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709165/
https://www.ncbi.nlm.nih.gov/pubmed/33269347
http://dx.doi.org/10.1101/2020.11.30.404905

Ejemplares similares