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Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain
Nucleocapsid protein (N) is the most abundant viral protein encoded by SARS-CoV-2, the causative agent of COVID-19. N plays key roles at different steps in the replication cycle and is used as a serological marker of infection. Here we characterize the biochemical properties of SARS-CoV-2 N. We defi...
Autores principales: | Wu, Chao, Qavi, Abraham J., Hachim, Asmaa, Kavian, Niloufar, Cole, Aidan R., Moyle, Austin B., Wagner, Nicole D., Sweeney-Gibbons, Joyce, Rohrs, Henry W., Gross, Michael L., Peiris, J. S. Malik, Basler, Christopher F., Farnsworth, Christopher W., Valkenburg, Sophie A., Amarasinghe, Gaya K., Leung, Daisy W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709165/ https://www.ncbi.nlm.nih.gov/pubmed/33269347 http://dx.doi.org/10.1101/2020.11.30.404905 |
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