Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis

Structural studies of glycoproteins and their complexes provide critical insights into their roles in normal physiology and disease. Most glycoproteins contain N-linked glycosylation, a key post-translation modification that critically affects protein folding and stability and the binding kinetics u...

Descripción completa

Detalles Bibliográficos
Autores principales: Kozak, Sandra, Bloch, Yehudi, De Munck, Steven, Mikula, Aleksandra, Bento, Isabel, Savvides, Savvas N., Meijers, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709199/
https://www.ncbi.nlm.nih.gov/pubmed/33263330
http://dx.doi.org/10.1107/S2059798320013753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709199/
https://www.ncbi.nlm.nih.gov/pubmed/33263330
http://dx.doi.org/10.1107/S2059798320013753

Ejemplares similares