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Increased prevalence of pfdhfr and pfdhps mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Jazan Region, Southwestern Saudi Arabia: important implications for malaria treatment policy

BACKGROUND: Despite significant progress in eliminating malaria from the Kingdom of Saudi Arabia, the disease is still endemic in the southwestern region of the country. Artesunate plus sulfadoxine–pyrimethamine (AS + SP) has been used in Saudi Arabia since 2007 as a first-line treatment for uncompl...

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Detalles Bibliográficos
Autores principales: Madkhali, Aymen M., Al-Mekhlafi, Hesham M., Atroosh, Wahib M., Ghzwani, Ahmad Hassn, Zain, Khalid Ammash, Abdulhaq, Ahmed A., Ghailan, Khalid Y., Anwar, Alkhansa A., Eisa, Zaki M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709338/
https://www.ncbi.nlm.nih.gov/pubmed/33267841
http://dx.doi.org/10.1186/s12936-020-03524-x