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Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands

BACKGROUND: The development and application of CRISPR technologies for the modification of the genome are rapidly expanding. Advances in the field describe new CRISPR components that are strategically engineered to improve the precision and reliability of CRISPR editing within the genome sequence. G...

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Detalles Bibliográficos
Autores principales: Farris, M. Heath, Texter, Pamela A., Mora, Agustin A., Wiles, Michael V., Mac Garrigle, Ellen F., Klaus, Sybil A., Rosfjord, Kristine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709351/
https://www.ncbi.nlm.nih.gov/pubmed/33267773
http://dx.doi.org/10.1186/s12864-020-07233-2