HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancer

BACKGROUND: Emerging evidence suggests that epithelial mesenchymal transition (EMT) and epigenetic mechanisms promote metastasis. Histone deacetylases (HDACs) and noncoding RNAs (ncRNAs) are important epigenetic regulators. Here, we elucidated a novel role of histone deacetylase 2 (HDAC2) in regulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Xue-ting, Xing, Wei, Zhao, Rong-sen, Tan, Yan, Wu, Xiao-feng, Ao, Luo-quan, Li, Zhan, Yao, Meng-wei, Yuan, Mu, Guo, Wei, Li, Shang-ze, Yu, Jian, Ao, Xiang, Xu, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709355/
https://www.ncbi.nlm.nih.gov/pubmed/33267897
http://dx.doi.org/10.1186/s13046-020-01783-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709355/
https://www.ncbi.nlm.nih.gov/pubmed/33267897
http://dx.doi.org/10.1186/s13046-020-01783-9

Ejemplares similares