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HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancer

BACKGROUND: Emerging evidence suggests that epithelial mesenchymal transition (EMT) and epigenetic mechanisms promote metastasis. Histone deacetylases (HDACs) and noncoding RNAs (ncRNAs) are important epigenetic regulators. Here, we elucidated a novel role of histone deacetylase 2 (HDAC2) in regulat...

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Detalles Bibliográficos
Autores principales:	Hu, Xue-ting, Xing, Wei, Zhao, Rong-sen, Tan, Yan, Wu, Xiao-feng, Ao, Luo-quan, Li, Zhan, Yao, Meng-wei, Yuan, Mu, Guo, Wei, Li, Shang-ze, Yu, Jian, Ao, Xiang, Xu, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709355/ https://www.ncbi.nlm.nih.gov/pubmed/33267897 http://dx.doi.org/10.1186/s13046-020-01783-9

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