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Fowl adenovirus (FAdV) fiber-based vaccine against inclusion body hepatitis (IBH) provides type-specific protection guided by humoral immunity and regulation of B and T cell response

A recombinant fowl adenovirus (FAdV) fiber protein, derived from a FAdV-8a strain, was tested for its efficacy to protect chickens against inclusion body hepatitis (IBH). FAdV-E field isolates belonging to both a homotypic (FAdV-8a) and heterotypic (-8b) serotype were used as challenge. Mechanisms u...

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Detalles Bibliográficos
Autores principales: De Luca, Carlotta, Schachner, Anna, Mitra, Taniya, Heidl, Sarah, Liebhart, Dieter, Hess, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709361/
https://www.ncbi.nlm.nih.gov/pubmed/33267862
http://dx.doi.org/10.1186/s13567-020-00869-8