Gestational arsenic exposure induces site-specific DNA hypomethylation in active retrotransposon subfamilies in offspring sperm in mice

BACKGROUND: Environmental impacts on a fetus can disrupt germ cell development leading to epimutations in mature germ cells. Paternal inheritance of adverse health effects through sperm epigenomes, including DNA methylomes, has been recognized in human and animal studies. However, the impacts of ges...

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Detalles Bibliográficos
Autores principales: Nohara, Keiko, Nakabayashi, Kazuhiko, Okamura, Kazuyuki, Suzuki, Takehiro, Suzuki, Shigekatsu, Hata, Kenichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709384/
https://www.ncbi.nlm.nih.gov/pubmed/33267854
http://dx.doi.org/10.1186/s13072-020-00375-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709384/
https://www.ncbi.nlm.nih.gov/pubmed/33267854
http://dx.doi.org/10.1186/s13072-020-00375-3

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