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Abelmoschus esculentus subfractions attenuate Aβ and tau by regulating DPP-4 and insulin resistance signals

BACKGROUND: Insulin resistance could be associated with the development of Alzheimer disease (AD). The neuropathological hallmarks of AD are beta amyloid (Aβ) produced from sequential cleavage initiated by β-secretase and degraded by insulin degradation enzyme (IDE), as well as hyperphosphorylation...

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Detalles Bibliográficos
Autores principales: Huang, Chien-Ning, Wang, Chau-Jong, Lin, Chih-Li, Li, Hsin-Hua, Yen, An-Ting, Peng, Chiung-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709418/
https://www.ncbi.nlm.nih.gov/pubmed/33267804
http://dx.doi.org/10.1186/s12906-020-03163-4