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Ice recrystallisation inhibiting polymers prevent irreversible protein aggregation during solvent-free cryopreservation as additives and as covalent polymer-protein conjugates

Protein storage and transport is essential to deliver therapies (biologics), enzymes for biotechnological applications, and underpins fundamental structural and molecular biology. To enable proteins to be stored and transported it is often essential to freeze them, requiring cryoprotectants such as...

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Detalles Bibliográficos
Autores principales: Fayter, Alice E.R., Hasan, Muhammad, Congdon, Thomas R., Kontopoulou, Ioanna, Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709485/
https://www.ncbi.nlm.nih.gov/pubmed/33311718
http://dx.doi.org/10.1016/j.eurpolymj.2020.110036