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Ice recrystallisation inhibiting polymers prevent irreversible protein aggregation during solvent-free cryopreservation as additives and as covalent polymer-protein conjugates
Protein storage and transport is essential to deliver therapies (biologics), enzymes for biotechnological applications, and underpins fundamental structural and molecular biology. To enable proteins to be stored and transported it is often essential to freeze them, requiring cryoprotectants such as...
Autores principales: | Fayter, Alice E.R., Hasan, Muhammad, Congdon, Thomas R., Kontopoulou, Ioanna, Gibson, Matthew I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709485/ https://www.ncbi.nlm.nih.gov/pubmed/33311718 http://dx.doi.org/10.1016/j.eurpolymj.2020.110036 |
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