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Histone deacetylase 6 inhibition in urothelial cancer as a potential new strategy for cancer treatment

Histone deacetylases (HDACs) are enzymes that remove acetyl groups from histones and have attracted attention as potential targets for cancer therapy. Several small molecule inhibitors have been developed to target HDACs; however, clinical trials of pan-HDAC inhibitors have found these types of inhi...

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Detalles Bibliográficos
Autores principales: Kuroki, Hiroo, Anraku, Tsutomu, Kazama, Akira, Shirono, Yuko, Bilim, Vladimir, Tomita, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709567/
https://www.ncbi.nlm.nih.gov/pubmed/33281975
http://dx.doi.org/10.3892/ol.2020.12315