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Matrix Remodeling and Hyaluronan Production by Myofibroblasts and Cancer-Associated Fibroblasts in 3D Collagen Matrices

The tumor microenvironment is a key modulator in cancer progression and has become a novel target in cancer therapy. An increase in hyaluronan (HA) accumulation and metabolism can be found in advancing tumor progression and are often associated with aggressive malignancy, drug resistance and poor pr...

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Detalles Bibliográficos
Autores principales: Sapudom, Jiranuwat, Müller, Claudia Damaris, Nguyen, Khiet-Tam, Martin, Steve, Anderegg, Ulf, Pompe, Tilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709683/
https://www.ncbi.nlm.nih.gov/pubmed/33008082
http://dx.doi.org/10.3390/gels6040033