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lncRNA GAS5 inhibits malignant progression by regulating macroautophagy and forms a negative feedback regulatory loop with the miR-34a/mTOR/SIRT1 pathway in colorectal cancer

Long non-coding RNA growth arrest specific 5 (GAS5) exerts inhibitory effects through the modulation of several target microRNAs (miRs) in cancer. However, its potential roles and underlying relationship during colorectal cancer (CRC) progression are unclear. Therefore, we explored the role of the n...

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Detalles Bibliográficos
Autores principales: Zhang, Hao-Gang, Wang, Fu-Jing, Wang, Yao, Zhao, Zi-Xing, Qiao, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709827/
https://www.ncbi.nlm.nih.gov/pubmed/33416133
http://dx.doi.org/10.3892/or.2020.7825