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Protein Arginine Methyltransferase PRMT5 Regulates Fatty Acid Metabolism and Lipid Droplet Biogenesis in White Adipose Tissues

The protein arginine methyltransferase 5 (PRMT5) is an emerging regulator of cancer and stem cells including adipogenic progenitors. Here, a new physiological role of PRMT5 in adipocytes and systemic metabolism is reported. Conditional knockout mice were generated to ablate the Prmt5 gene specifical...

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Detalles Bibliográficos
Autores principales: Jia, Zhihao, Yue, Feng, Chen, Xiyue, Narayanan, Naagarajan, Qiu, Jiamin, Syed, Sabriya A., Imbalzano, Anthony N., Deng, Meng, Yu, Peng, Hu, Changdeng, Kuang, Shihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709973/
https://www.ncbi.nlm.nih.gov/pubmed/33304767
http://dx.doi.org/10.1002/advs.202002602