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Loss of β‐Actin Leads to Accelerated Mineralization and Dysregulation of Osteoblast‐Differentiation Genes during Osteogenic Reprogramming

Actin plays fundamental roles in both the cytoplasm and the cell nucleus. In the nucleus, β‐actin regulates neuronal reprogramming by consolidating a heterochromatin landscape required for transcription of neuronal gene programs, yet it remains unknown whether it has a role in other differentiation...

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Detalles Bibliográficos
Autores principales: Gjorgjieva, Tamara, Xie, Xin, Commins, Patrick, Pasricha, Renu, Mahmood, Syed Raza, Gunsalus, Kristin C., Naumov, Panče, Percipalle, Piergiorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709978/
https://www.ncbi.nlm.nih.gov/pubmed/33304760
http://dx.doi.org/10.1002/advs.202002261