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Assessing methods to quantitatively validate TGFβ-dependent autophagy

Transforming growth factor beta (TGFβ) promotes tumorigenesis by suppressing immune surveillance and inducing epithelial to mesenchymal transition (EMT). TGFβ may augment tumorigenesis by activating autophagy, which protects cancer cells from chemotherapy and promotes invasive and anti-apoptotic pro...

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Detalles Bibliográficos
Autores principales: Trelford, Charles B., Di Guglielmo, Gianni M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710024/
https://www.ncbi.nlm.nih.gov/pubmed/33168592
http://dx.doi.org/10.1242/bio.055103