The DNA damage response is required for oocyte cyst breakdown and follicle formation in mice

Mammalian oogonia proliferate without completing cytokinesis, forming cysts. Within these, oocytes differentiate and initiate meiosis, promoting double-strand break (DSBs) formation, which are repaired by homologous recombination (HR) causing the pairing and synapsis of the homologs. Errors in these...

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Detalles Bibliográficos
Autores principales: Martínez-Marchal, Ana, Huang, Yan, Guillot-Ferriols, Maria Teresa, Ferrer-Roda, Mònica, Guixé, Anna, Garcia-Caldés, Montserrat, Roig, Ignasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710113/
https://www.ncbi.nlm.nih.gov/pubmed/33206637
http://dx.doi.org/10.1371/journal.pgen.1009067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710113/
https://www.ncbi.nlm.nih.gov/pubmed/33206637
http://dx.doi.org/10.1371/journal.pgen.1009067

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