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Systems biology informed deep learning for inferring parameters and hidden dynamics

Mathematical models of biological reactions at the system-level lead to a set of ordinary differential equations with many unknown parameters that need to be inferred using relatively few experimental measurements. Having a reliable and robust algorithm for parameter inference and prediction of the...

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Detalles Bibliográficos
Autores principales: Yazdani, Alireza, Lu, Lu, Raissi, Maziar, Karniadakis, George Em
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710119/
https://www.ncbi.nlm.nih.gov/pubmed/33206658
http://dx.doi.org/10.1371/journal.pcbi.1007575