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Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25

Grafted mesenchymal stem cells (MSCs) yield neuroprotection in preclinical stroke models by secreting extracellular vesicles (EVs). The neuroprotective cargo of EVs, however, has not yet been identified. To investigate such cargo and its underlying mechanism, primary neurons were exposed to oxygen‐g...

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Detalles Bibliográficos
Autores principales: Kuang, Yaoyun, Zheng, Xuan, Zhang, Lin, Ai, Xiaoyu, Venkataramani, Vivek, Kilic, Ertugrul, Hermann, Dirk M., Majid, Arshad, Bähr, Mathias, Doeppner, Thorsten R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710129/
https://www.ncbi.nlm.nih.gov/pubmed/33304476
http://dx.doi.org/10.1002/jev2.12024