Cargando…
Adipose‐derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR‐25
Grafted mesenchymal stem cells (MSCs) yield neuroprotection in preclinical stroke models by secreting extracellular vesicles (EVs). The neuroprotective cargo of EVs, however, has not yet been identified. To investigate such cargo and its underlying mechanism, primary neurons were exposed to oxygen‐g...
Autores principales: | Kuang, Yaoyun, Zheng, Xuan, Zhang, Lin, Ai, Xiaoyu, Venkataramani, Vivek, Kilic, Ertugrul, Hermann, Dirk M., Majid, Arshad, Bähr, Mathias, Doeppner, Thorsten R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710129/ https://www.ncbi.nlm.nih.gov/pubmed/33304476 http://dx.doi.org/10.1002/jev2.12024 |
Ejemplares similares
-
Extracellular vesicles from hypoxia-preconditioned microglia promote angiogenesis and repress apoptosis in stroke mice via the TGF-β/Smad2/3 pathway
por: Zhang, Lin, et al.
Publicado: (2021) -
Lithium modulates miR‐1906 levels of mesenchymal stem cell‐derived extracellular vesicles contributing to poststroke neuroprotection by toll‐like receptor 4 regulation
por: Haupt, Matteo, et al.
Publicado: (2020) -
Neural Progenitor Cell-Derived Extracellular Vesicles Enhance Blood-Brain Barrier Integrity by NF-κB (Nuclear Factor-κB)-Dependent Regulation of ABCB1 (ATP-Binding Cassette Transporter B1) in Stroke Mice
por: Zhang, Lin, et al.
Publicado: (2020) -
Inhibition of Fatty Acid Synthesis Aggravates Brain Injury, Reduces Blood-Brain Barrier Integrity and Impairs Neurological Recovery in a Murine Stroke Model
por: Janssen, Lisa, et al.
Publicado: (2021) -
Concise Review: Extracellular Vesicles Overcoming Limitations of Cell Therapies in Ischemic Stroke
por: Doeppner, Thorsten R., et al.
Publicado: (2017)