Deficiency of Notch signaling in pericytes results in arteriovenous malformations

Arteriovenous malformations (AVMs) are high-flow lesions directly connecting arteries and veins. In the brain, AVM rupture can cause seizures, stroke, and death. Patients with AVMs exhibit reduced coverage of the vessels by pericytes, the mural cells of microvascular capillaries; however, the mechan...

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Detalles Bibliográficos
Autores principales: Nadeem, Taliha, Bogue, Wil, Bigit, Bianca, Cuervo, Henar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710269/
https://www.ncbi.nlm.nih.gov/pubmed/33148887
http://dx.doi.org/10.1172/jci.insight.125940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710269/
https://www.ncbi.nlm.nih.gov/pubmed/33148887
http://dx.doi.org/10.1172/jci.insight.125940

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