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A soluble activator that favors the ex vivo expansion of CD8(+)CD27(+) T cells

Adoptive cell therapy involves the infusion of tumor-reactive T cells into patients with cancer to provide antitumor immunity. The ex vivo expansion and differentiation of such T cells are key parameters that affect their therapeutic potential. Human T cells are presently expanded in culture through...

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Detalles Bibliográficos
Autores principales:	Matus, Esther I., Sparkes, Amanda, Gariépy, Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2020
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710272/ https://www.ncbi.nlm.nih.gov/pubmed/33208551 http://dx.doi.org/10.1172/jci.insight.141293

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