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PDGFRA in vascular adventitial MSCs promotes neointima formation in arteriovenous fistula in chronic kidney disease

Chronic kidney disease (CKD) induces the failure of arteriovenous fistulas (AVFs) and promotes the differentiation of vascular adventitial GLI1-positive mesenchymal stem cells (GMCs). However, the roles of GMCs in forming neointima in AVFs remain unknown. GMCs isolated from CKD mice showed increased...

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Detalles Bibliográficos
Autores principales: Song, Ke, Qing, Ying, Guo, Qunying, Peden, Eric K., Chen, Changyi, Mitch, William E., Truong, Luan, Cheng, Jizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710276/
https://www.ncbi.nlm.nih.gov/pubmed/33001865
http://dx.doi.org/10.1172/jci.insight.137298