Acarbose has sex-dependent and -independent effects on age-related physical function, cardiac health, and lipid biology

With an expanding aging population burdened with comorbidities, there is considerable interest in treatments that optimize health in later life. Acarbose (ACA), a drug used clinically to treat type 2 diabetes mellitus (T2DM), can extend mouse life span with greater effect in males than in females. U...

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Detalles Bibliográficos
Autores principales: Herrera, Jonathan J., Louzon, Sean, Pifer, Kaitlyn, Leander, Danielle, Merrihew, Gennifer E., Park, Jea H., Szczesniak, Kate, Whitson, Jeremy, Wilkinson, John E., Fiehn, Oliver, MacCoss, Michael J., Day, Sharlene M., Miller, Richard A., Garratt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710286/
https://www.ncbi.nlm.nih.gov/pubmed/32990683
http://dx.doi.org/10.1172/jci.insight.137474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710286/
https://www.ncbi.nlm.nih.gov/pubmed/32990683
http://dx.doi.org/10.1172/jci.insight.137474

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