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Acarbose has sex-dependent and -independent effects on age-related physical function, cardiac health, and lipid biology
With an expanding aging population burdened with comorbidities, there is considerable interest in treatments that optimize health in later life. Acarbose (ACA), a drug used clinically to treat type 2 diabetes mellitus (T2DM), can extend mouse life span with greater effect in males than in females. U...
Autores principales: | Herrera, Jonathan J., Louzon, Sean, Pifer, Kaitlyn, Leander, Danielle, Merrihew, Gennifer E., Park, Jea H., Szczesniak, Kate, Whitson, Jeremy, Wilkinson, John E., Fiehn, Oliver, MacCoss, Michael J., Day, Sharlene M., Miller, Richard A., Garratt, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7710286/ https://www.ncbi.nlm.nih.gov/pubmed/32990683 http://dx.doi.org/10.1172/jci.insight.137474 |
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